Recombinant Proteins in Escherichia coli: Optimizing Production Strategies
نویسندگان
چکیده
The recombinant proteins are under special attention due to their medical, pharmaceutical and industrial uses. Bacteria are simple and cost effective hosts for producing recombinant proteins. The Gram-negative bacterium Escherichia coli is a high yielding recombinant protein production system, due to its specific characteristics such as the rapid and high-density growth, need of poor medium and known genome. In this review, we examine the factors involved in the production of recombinant proteins by E. coli, focusing on the optimization of strategies responsible for the improvement of yield.
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تاریخ انتشار 2016